Microfluidic liver chips

Drs. Rajagopalan and Davalos are seeking to build and culture a miniaturized version of the in vitro 3D liver mimic within a microfluidic chip. The microfluidic liver mimic will be a complete dynamic 3D liver model on chip that will enable metabolic monitoring for hepatotoxic assays. This liver-on-chip will facilitate the characterization and quantification of liver response to different oxygen and drug concentrations dynamically and at a high temporal resolution.